Withania somnifera (Ashawagandha) is very revered herb of the Indian Ayurvedic system of medicine as a Rasayana (tonic). It is used for various kinds of disease processes and specially as a nervine tonic. Ashwagandha is a well-known adaptogen and known for reducing stress and anxiety in humans.

Longjack increases the body's release of DHEA, dihydrotestosterone, and lowers SHBG. Longjack has also been shown to increase muscle size and strength, improve overall well being, accelerate recovery from exercise, enhance weight loss, reduce stress, and reduce symptoms of fatigue. Longjack decreased salivary free cortisol in stressed participants.

T. Terrestris increases LH which increases circulating androgens and estrogens. T. Terrestris has been shown to improve hypoactive sexual disorder in females and sexual desire in males. T. Terrestris has positive effects on blood glucose and lipids. T. Terrestris may improve exercise performance. T. Terrestris has anti-inflammatory properties.

Stinging Nettle binds to Sex Hormone Binding Globulin (SHBG) thus increasing the blood concentration of bioactive androgens and estrogens. Stinging Nettle helps relieve symptoms of BPH. Stinging Nettle displays antioxidant immunomodulatory, and anti-inflammatory properties and lowers blood lipids.

Provides a source of L-DOPA which increases dopamine and epinephrine. Dopamine then goes on to increase testosterone and estrogen levels by increasing GnRH. Also decreases PRL which functions to help increase GnRH. Leads to an increase in AR activation through L-Dopa decarboxylase. Velvet bean posses antioxidant, anti-inflammatory, and anti-diabetic properties.

Blocks the conversion of testosterone to estrogen by inhibiting the aromatase enzyme. Also increases the androgen precursors to estrogen by inhibiting aromatase. Possess anti inflammatory and antioxidant properties. Lowers plasma free fatty acids, triglycerides, and lipoproteins. Also lowers cholesterol biosynthesis35 Grape seed extract increases the production of nitric oxide which improves blood flow.

Shifts the metabolism of estrogen from 16HE to 2HE which decreases the risk of estrogen-related cancers. Decreases ERɑ receptors in breast tissue and has other anti-neoplastic properties. Clinical studies with DIM show clinical improvement in cervical cancer and vulvular intraepithelial neoplasia (VIN). DIM induces anti-neoplastic functions of the immune system. DIM decreased fat accumulation in adipocytes while simultaneously lowering triglycerides, insulin, leptin and increasing adiponectin.

Helps the liver metabolize estrogen by assisting in methylation. Betaine helps prevent hypomethylation in low estrogen states like menopause. Betaine prevents choline deficiency in low estrogen states which can lead to fatty liver disease. Betaine helps regulate cell volume and stabilizes intracellular proteins. Betaine improves energy metabolism by supporting the synthesis of carnitine which increases fatty acid oxidation. Betaine improves athletic performance and insulin signaling, and lowers body fat while increasing lean muscle mass.

Ginseng has beneficial antioxidant and anti-inflammatory properties. Ginseng may improve symptoms of erectile dysfunction by decreasing oxidative stress in tissues and enhancing blood flow in penile muscles. The men then had levels of certain inflammatory markers tested after performing an exercise test. These levels were significantly lower than in the placebo group, lasting for up to 72 hours after testing. One study found that men treated with Korean red ginseng had a 60% improvement in ED symptoms, compared to 30% improvement produced by a medication used to treat ED. Research has shown that ginseng may be a useful alternative for the treatment of erectile dysfunction (ED) in men. It seems that compounds in it may protect against oxidative stress in blood vessels and tissues in the penis and help restore normal function. Additionally, studies have shown that ginseng may promote the production of nitric oxide, a compound that improves muscle relaxation in the penis and increases blood circulation. Moreover, another study showed that 86 men with ED had significant improvements in erectile function and overall satisfaction after taking 1,000 mg of aged ginseng extract for 8 weeks.